Hereditary angioedema yog kab mob caj ces uas tshwm sim vim muaj qhov tsis xws lossis hloov pauv hauv cov noob uas tswj C1-inhibitor, thiab tsis tshua muaj kab mob, cuam tshuam rau 1 hauv 50, 000 tus neeg. Cov neeg txom nyem ntawm tus kab mob no yuav muaj qhov o tuaj piav tsis tau hauv qhov kawg, thiab kuj tseem yuav muaj kev mob plab thiab mob plab uas zoo li tuaj yam tsis muaj lus piav qhia. Hmoov zoo, muaj cov kev kho mob uas tuaj yeem pab cov neeg kuaj mob tus kab mob, tab sis kev kuaj mob tsis raug yog ib txwm muaj. Yog li ntawd, nws yog ib qho tseem ceeb kom nkag siab tias cov tsos mob yog dab tsi, thiab yuav txheeb xyuas tus kab mob li cas. Angioedema tuaj yeem ua rau tuag taus. Hu rau 911 rau kev saib xyuas xwm txheej ceev yog tias koj lub caj pas pib o lossis yog koj ua pa nyuaj.
Cov kauj ruam
Ntu 1 ntawm 3: Txheeb Xyuas Kab Mob Angioedema
Kauj Ruam 1. Txheeb xyuas koj tsev neeg keeb kwm
Qhov teeb meem no yog autosomal tseem ceeb. Qhov no txhais tau tias yog ib qho ntawm koj niam koj txiv lossis lwm tus neeg hauv tsev neeg muaj nws ib yam. Yog tias koj tau txais yuav thiab txhawj xeeb txog qhov muaj teeb meem no, koj tuaj yeem tuaj yeem tau txais kev kuaj mob caj ces.
Kauj Ruam 2. Nco tseg ntawm koj cov tsos mob
Hmoov tsis zoo, cov tsos mob ntawm tus mob angioedema feem ntau tsis meej pem nrog lwm yam kab mob ntau dua. Yog li, tus kab mob no feem ntau kuaj pom tsis raug. Koj tus kws kho mob yuav ua ntau qhov kev xeem txhawm rau txiav tawm lwm yam teeb meem hauv qab.
Cov tsos mob tshwm sim ntawm tus kab mob angioedema muaj xws li: ua pa hauv caj pas uas ua rau nws ua pa nyuaj thiab/lossis tham, mob plab hauv plab vim tsis paub meej vim li cas, piav tsis tau o ntawm qhov qis (piv txwv li caj npab, ob txhais ceg, chaw mos, tus nplaig, thiab lwm yam), thiab/lossis pob liab liab ntawm qhov tawv nqaij uas tsis khaus
Kauj Ruam 3. Tham nrog koj tus kws kho mob
Tib txoj hauv kev los kuaj mob caj ces angioedema txhais tau meej yog kom kuaj ntshav los ntawm kws kho mob. Yog li, koj yuav tsum tau mus ntsib koj tus kws kho mob thiab tham txog qhov teeb meem nrog lawv. Piav qhia rau koj tus kws kho mob nws yog dab tsi uas ua rau koj xav tias koj muaj keeb kwm mob angioedema.
- Nqa cov tshuaj uas koj tab tom noj. Nws yuav tsis muaj feem cuam tshuam, tab sis koj tsis tuaj yeem ntseeg tau; yog li ntawd, nws yog qhov zoo tshaj los nqa koj cov tshuaj hauv lawv lub raj mis qub kom koj tus kws kho mob muaj txhua yam ntaub ntawv tsim nyog txog koj cov tshuaj.
- Sau cov ntaub ntawv uas koj xav tias yuav pab tau. Piv txwv li, ib qho tsos mob uas koj tau muaj uas kws kho mob tsis tuaj yeem txheeb xyuas qhov ua rau. Ib qho piv txwv ntawm cov tsos mob tshwm sim yog mob plab uas tsis muaj qhov ua rau pom tseeb.
Kauj Ruam 4. Mus kuaj ntshav
Tib txoj hauv kev los kuaj tus kab mob no yog los ntawm kev kuaj ntshav. Kev kuaj ntshav tsuas ua haujlwm thaum lub sijhawm ua kom koj cov tsos mob hnyav. Koj tus kws kho mob yuav xaj qhov kev sim no yog tias lawv xav tias mob angioedema ua rau koj cov tsos mob. Tshwj xeeb, kev kuaj ntshav yuav tsum ntsuas C1-inhibitor muaj nuj nqi thiab qib, nrog rau qib C4 hauv koj cov ntshav.
Qhov zoo tshaj, kev kuaj ntshav yuav ua thaum lub sijhawm rov tshwm sim (piv txwv li lub sijhawm thaum koj tab tom muaj cov tsos mob xws li mob thiab/lossis o)
Ntu 2 ntawm 3: Kho Tus Mob Angioedema
Kauj Ruam 1. Hu rau 911 yog tias koj lub caj pas pib o
Yog tias koj pib ua pa nyuaj lossis yog koj lub caj pas pib o, hu rau 911 rau kev saib xyuas xwm txheej tam sim. Nov yog qhov xwm txheej txaus ntshai rau lub neej, thiab koj yuav xav tau kev kho mob tam sim.
Kauj Ruam 2. Tsis txhob noj tshuaj antihistamines rau cov tsos mob uas piav tsis tau
Hmoov tsis zoo, cov tsos mob ntawm tus mob angioedema tsis teb rau cov tshuaj antihistamines. Yog tias koj tseem tsis tau kuaj pom, ntau tus kws kho mob yuav sau tshuaj antihistamine ua txoj hauv kev kho koj tus tsos mob.
Thaum muaj xwm txheej ceev, epinephrine tuaj yeem siv los kho ib tus neeg uas muaj keeb kwm mob angioedema. Piv txwv li, yog tias lawv ua tsis taus pa vim yog txoj hlab ntsws o
Kauj Ruam 3. Xaiv txoj kev kho mob raws koj hom mob angioedema
Raws li xyoo 2016, muaj tsib txoj kev kho mob rau tus mob angioedema uas tau pom zoo los ntawm US Food and Drug Administration (FDA). Qee qhov kev kho mob no tau muab tso rau hauv cov hlab ntshav (piv txwv li dhau los ntawm IV) thaum lwm tus raug txhaj tshuaj. Cov neeg feem coob uas muaj tus mob angioedema tuaj yeem tswj hwm cov kev kho no lawv tus kheej, hauv kev yooj yim ntawm lawv lub tsev.
- Qhov kev xaiv kho mob uas yuav zoo tshaj rau koj yog nyob ntawm koj qhov xwm txheej tshwj xeeb. Yog tias koj muaj C1-inhibitor tsis ua haujlwm, piv txwv li, koj tus kws kho mob yuav sau ntawv rau koj Cinryze, Berinert, lossis Ruconest, uas txhua yam ua haujlwm los pab koj li C1-inhibitor muaj nuj nqi.
- Nco ntsoov nrog koj tus kws kho mob tham txog qhov zoo thiab qhov tsis zoo ntawm txhua yam tshuaj. Cov tshuaj no tuaj nrog lawv tus kheej cov kev mob tshwm sim tsis zoo, yog li koj yuav tsum saib xyuas koj kev noj qab haus huv ua tib zoo saib xyuas thaum siv tshuaj kho mob.
Kauj Ruam 4. Ua tshwj xeeb rau cov menyuam
Ntau yam kev kho mob muaj tsis tau pom zoo siv rau menyuam yaus hnub nyoog qis dua 12 xyoos. Yog li ntawd, yog tias koj tus menyuam muaj keeb kwm angioedema, koj yuav tsum tau nrhiav kev kho mob sib txawv. Nco ntsoov tias cov neeg laus uas siv sijhawm nrog koj cov menyuam sab nraum koj lub xub ntiag paub txog koj tus menyuam tus mob, thiab lawv yuav tsum ua dab tsi thaum muaj kev tawm tsam.
- Raws li xyoo 2016, tsuas yog siv tshuaj pom zoo rau cov menyuam hnub nyoog qis dua 12 xyoos yog Berinert.
- Lub koom haum Asmeskas cov neeg mob angioedema (HAEA) muab cov ntawv qhia muaj txiaj ntsig thiab cov ntaub ntawv uas koj tuaj yeem muab rau cov neeg laus uas muaj lub luag haujlwm rau koj tus menyuam (piv txwv li kws qhia ntawv, tsev neeg phooj ywg, kws qhia, thiab lwm yam). Lub vev xaib rau cov ntaub ntawv no yog
Ntu 3 ntawm 3: Nkag Siab Hereditary Angioedema
Kauj Ruam 1. Kawm paub txog kev mob qog noj ntshav angioedema
Qhov pom tseeb tshaj plaws uas tshwm sim hauv tus neeg uas muaj keeb kwm mob angioedema yog o hauv qab daim tawv nqaij. Qhov o feem ntau tshwm sim hauv plab, qhov chaw mos, lossis lub caj pas thiab qhov ncauj. Qhov no tshwm sim vim yog C1-inhibitor uas tsis ua haujlwm zoo. C1-inhibitor tswj cov protein hauv cov ntshav hu ua C1. Ua ke nrog lub cev tiv thaiv kab mob, C1 ib txwm tswj hwm cov lus teb hauv lub cev. Yog li, yog tias C1-inhibitor tsis ua haujlwm zoo, tsis yog C1 protein.
- Muaj qee qhov tshwm sim uas zoo li ua rau muaj cov tsos mob tshwm sim ntau dua. #*Piv txwv li, cev xeeb tub thiab cev xeeb tub, pub niam mis, thiab siv tshuaj tiv thaiv menyuam yaus lossis kho tshuaj hloov tshuaj poj niam rau txhua tus zoo li ua ntu ntu tshwm sim ntau dua.
- Lwm qhov tshwm sim zoo li tshwm sim los ntawm txheej txheem kho hniav lossis siv ACE inhibitors, uas feem ntau tau sau tseg los kho ntshav siab.
Kauj Ruam 2. Nkag siab tias tus kab mob no feem ntau yog caj ces
Henditary angioedema yuav luag ib txwm tshwm sim los ntawm kev tshuaj ntsuam tsis zoo uas dhau los ntawm niam txiv mus rau tus menyuam. Ob peb kis ntawm kev hloov pauv tshwm sim ntawm cov noob uas tswj C1-inhibitor tau tshwm sim. Qhov kev hloov pauv tshwm sim tshwm sim ntawm kev xeeb tub. Txawm hais tias koj kis tau tshwm sim los ntawm kev tsis zoo ntawm caj ces lossis hloov pauv ntawm tus kheej, koj muaj 50% txoj hauv kev kis tus kabmob mus rau ib tus menyuam uas koj muaj.
Qhov no tsis txhais tau tias koj yuav tsum tsis txhob muaj menyuam. Txawm li cas los xij, nws yog ib qho tseem ceeb los tham txog kev npaj tsev neeg nrog koj tus kws kho mob yog tias koj muaj keeb kwm mob angioedema txhawm rau nkag siab qhov txaus ntshai
Kauj Ruam 3. Ceev faj tias tus kab mob no feem ntau kuaj mob tsis raug
Kev muaj mob angioedema tshwm sim hauv kwv yees li 1 ntawm 50, 000 tus neeg, ua rau tus kab mob no tsawg heev. Vim li no, thiab vim tias cov tsos mob feem ntau yuam kev rau lwm qhov, ntau qhov teeb meem, ntau tus neeg muaj tus kab mob mus ntau xyoo yam tsis tau txais kev kuaj mob kom raug. Hmoov tsis zoo, qhov no kuj tseem coj cov neeg muaj tus kab mob mus rau txoj kev ntev thiab nyuaj siab vim tias lawv tsis tuaj yeem nrhiav txoj hauv kev los tswj tus kab mob vim tias lawv tsis paub tias lawv muaj.
