T Cell kho mob qog noj ntshav yog kev kho mob tshiab uas cuam tshuam nrog kev siv tus neeg mob tus kheej lub cev tiv thaiv kab mob los tawm tsam mob qog noj ntshav. Muaj ob peb hom kev kho mob qog noj ntshav T Cell xws li kev kho tus mob saws me nyuam (ACT), qog nqaij hlav hauv cov qog ntshav lymphocytes (TIL), thiab T cell kho nrog chimeric antigen receptors (CARs). T Cell kho tau siv zoo heev hauv kev sim tshuaj nrog ntau yam qog ntshav qog ntshav xws li mob qog noj ntshav lymphoblastic. Muab qhov kev pheej hmoo loj koom nrog hauv T Cell kho, koj yuav tsum tsuas yog koom nrog hauv kev sim tshuaj yog tias koj tau siv tag nrho lwm txoj kev kho mob.
Cov kauj ruam
Txoj Kev 1 ntawm 2: Tshawb Fawb Kev Kuaj
Kauj Ruam 1. Tshawb nrhiav seb puas muaj kev sim tshuaj kho mob hauv koj cheeb tsam
Koj yuav tsum txiav txim siab seb puas muaj kev sim T Cell kho mob qog noj ntshav hauv koj lub tebchaws lossis thaj av, vim tsuas muaj qee qhov kev tshawb fawb tseem tab tom ua. Muab qhov tsawg ntawm cov kev sim tam sim no tab tom kho rau qhov kev kho mob no thiab txwv qhov chaw (xws li Tebchaws Askiv thiab Tebchaws Meskas), nws yuav nyuaj rau kev nyab xeeb kev koom nrog hauv ib qho ntawm cov kev sim no.
Kauj Ruam 2. Nug lub koom haum mob qog noj ntshav txog kev sim
Koj yuav tsum hu rau kws kho mob tshwj xeeb xws li kws tshawb fawb, kws kho mob hauv tsev kawm qib siab lossis pab pawg mob qog noj ntshav uas tsom mus rau koj hom mob qog noj ntshav tshwj xeeb. Qee pab pawg txhawb nqa rau qee hom mob qog noj ntshav muaj cov ntaub ntawv xov xwm uas yuav muab tswv yim rau koj txog kev sim tshuaj hauv xov tooj.
- Piv txwv li, Leukemia thiab Lymphoma Society muaj xov tooj xov tooj uas muab tswv yim rau cov neeg mob qog noj ntshav. Hu: 800-955-4572.
- Koj tuaj yeem tshawb nrhiav National Cancer Institute txhawb kev sim tshuaj ntawm lawv lub vev xaib ntawm:
- Yog tias muaj tsev kawm qib siab loj hauv koj cheeb tsam, koj tuaj yeem tiv toj rau lub chaw kho mob thiab nug txog ib qho kev sim tshuaj kho mob twg uas tseem tab tom ua ntawm lub tsev ntawd.
Kauj Ruam 3. Nug cov kws tshawb fawb txog kev kho mob
Yog tias koj tau txais chimeric antigen receptor T-Cell kho, cov kws kho mob yuav siv ntshav los ntawm koj lub cev txhawm rau rho T cells, uas tau xa mus rau chav kuaj ntshav. Koj lub T-cells yuav raug tsim los ntawm caj ces los tsim cov chimeric antigen receptors ntau dua (CARs), uas yuav ua rau koj lub cev T cells nkag mus rau cov qog nqaij hlav. Tom qab CAR T-cells tau muab tso rau hauv chav kuaj ntshav, lawv yuav rov nkag rau hauv koj lub cev ntawm chaw kho mob. Muab qhov nyuaj ntawm kev kho mob no, koj yuav tsum nug koj tus kws kho mob txog cov ncauj lus kom ntxaws:
- "Kuv yuav nyob hauv tsev kho mob ntev npaum li cas?"
- "Yuav siv cov ntshav ntau npaum li cas?"
- "Kuv yuav tau tos ntev npaum li cas thaum kuv T-cells nyob tom chav kuaj?"
- "Nws yuav hnov zoo li cas thaum T-cells rov qab nkag rau hauv kuv lub cev?"
Kauj Ruam 4. Kawm paub txog qhov tshwm sim muaj tshwm sim
Koj yuav tsum paub tias T Cell kev kho mob qog noj ntshav tuaj yeem cuam tshuam nrog cov kev mob tshwm sim loj heev, uas feem ntau siv ntau tus kws tshaj lij kho mob kom tswj tau. Txawm hais tias kev tshawb fawb tseem tab tom txo qhov hnyav ntawm kev phiv, koj yuav tsum paub tias qhov kev kho mob no tsuas yog muaj txiaj ntsig yog tias koj tau siv lwm txoj hauv kev. Yog koj xaiv nws, koj yuav tsum paub txog qee yam kev phiv. Piv txwv li, cov kev mob tshwm sim ntawm CAR T-Cell kev kho mob suav nrog:
- Cytokine tso tawm cov tsos mob, uas tuaj yeem ua rau kub taub hau, ntshav qis, ua haujlwm tsis zoo ntawm lub ntsws thiab lwm yam tsos mob hnyav.
- B-cell aplasia, uas rhuav tshem cov qe B qub hauv koj cov ntshav.
- Tumor Lysis syndrome, uas yog qhov ua rau muaj kev phom sij rau lub neej. Qhov no yog qhov phom sij txaus ntshai tab sis tuaj yeem tswj tau zoo.
Txoj Kev 2 ntawm 2: Ua Haujlwm Nrog Koj Tus Kws Kho Mob
Kauj Ruam 1. Tshawb xyuas seb koj puas siv cov txheej txheem kev kho mob tag
Kev phais, tshuaj kho mob thiab kho hluav taws xob tseem yog lub hauv paus rau kev kho mob qog noj ntshav ntau. Txawm hais tias kev tshawb fawb txog T Cell txoj kev kho mob qog noj ntshav tau cog lus zoo, hom kev kho mob no nyuam qhuav dhau los ua kev sim rau tib neeg thiab tseem tsis tau txais kev pom zoo los ntawm tseem hwv hauv Tebchaws Meskas Yog li, koj yuav tsum paub tseeb tias koj tau tshawb nrhiav txhua qhov qauv kev kho mob rau koj hom ntawm mob qog noj ntshav. Feem ntau, cov kws kho mob tsuas yog tso cai rau koj koom nrog hauv cov kev sim no yog tias txhua qhov kev xaiv tau ua tiav nrog tsis ua tiav. Nug koj tus kws kho mob:
- "Peb puas tau tshawb nrhiav txhua txoj kev kho mob rau kuv mob qog noj ntshav?"
- "Koj puas xav tias peb nyob ntawm qhov chaw uas kuv yuav tsum tau saib xyuas kev sim tshuaj?"
Kauj Ruam 2. Nug koj tus kws kho mob txog T Cell Cancer Trials
Koj tus kws kho mob yuav muaj cov npoj yaig uas tab tom kho T Cell kho mob qog noj ntshav, yog li koj yuav tsum nug lawv tias lawv paub leej twg thiab koj yuav koom nrog li cas. Sim nug:
- "Koj puas paub leej twg koom nrog hauv T Cell tshawb fawb mob qog noj ntshav?"
- "Koj puas xav tias koj tuaj yeem pab kuv cuv npe hauv T Cell kev kho mob qog noj ntshav?"
- "Cov kev pheej hmoo ntawm kev koom nrog ib qho ntawm cov kev sim no yog dab tsi?"
Kauj Ruam 3. Xav txog cov txiaj ntsig ntawm kev koom nrog hauv T Cell txoj kev kho mob qog noj ntshav
Ntawm tus ntawv sau lossis ntaus ntawv, sau tag nrho cov txiaj ntsig tau uas koj tuaj yeem pom los ntawm kev koom nrog hauv kev sim. Cov txiaj ntsig tshawb fawb thaum ntxov tau cog lus zoo txog kev ua haujlwm ntawm T Cell kho mob qog noj ntshav. Ib qho txiaj ntsig ntawm kev koom nrog hauv kev sim yog tias koj yuav yog thawj tus tau txais txiaj ntsig los ntawm kev kho mob qog noj ntshav tshiab thiab zoo dua. Koj kuj tseem yuav tau txais txiaj ntsig ntawm kev tshuaj xyuas ntxiv tom qab kev sim. Ib qho ntxiv, koj yuav pab tib neeg nrhiav kev kho mob qog noj ntshav.
Kauj Ruam 4. Sau tag nrho cov kev pheej hmoo
Qhov tsis zoo ntawm kev koom nrog hauv kev sim tshuaj suav nrog qhov tseeb tias kev kho mob tshiab, T Cell kho, yuav tsis zoo li kev kho mob qog noj ntshav qub. Ib qho ntxiv, txawm tias kev kho mob tshiab zoo dua rau tib neeg feem ntau, nws yuav tsis zoo dua rau koj lub cev tshwj xeeb. Thaum kawg, koj yuav ntsib ntau yam kev phiv los ntawm T Cell kho mob qog noj ntshav xws li cytokine tso tawm syndrome thiab B cell aplasia. Nws tseem yuav yog lub sijhawm zoo nkauj heev thiab ua rau lub siab qaug zog.
Kauj Ruam 5. Xaiv seb puas yuav koom nrog hauv kev sim
Koj yuav tsum ntsuas qhov txiaj ntsig thiab txaus ntshai ntawm kev koom nrog T Cell kev kho mob qog noj ntshav, thiab tom qab ntawd txiav txim siab paub.
Kauj Ruam 6. Mus dhau cov txheej txheem tso cai pom zoo
Yog tias koj ntsuas qhov txiaj ntsig thiab txaus ntshai thiab tseem xav koom nrog hauv T Cell txoj kev kho mob qog noj ntshav, koj yuav tsum tau mus dhau qhov kev pom zoo pom zoo. Koj tus kws kho mob yuav qhia koj txog txhua yam tshwj xeeb thiab txiaj ntsig ntawm kev sim. Koj yuav tsum nug cov lus nug uas koj muaj txog kev sim siab. Xav paub thiab nug ntau cov lus nug txog cov txiaj ntsig, txaus ntshai, phiv thiab lwm yam ntsiab lus ntawm kev koom nrog hauv kev sim.
Kauj Ruam 7. Ruaj ntseg kev pab tu tus neeg saib xyuas lub sijhawm mus sib hais
Nrhiav tus kws saib xyuas kev noj qab haus huv los pab koj rau lub sijhawm sim tshuaj kho mob. Txawm hais tias qhov no tsis yog ib txwm xav tau los ntawm kev sim, nws yog qhov kev tiv thaiv zoo vim tias qhov kev sim siab ntawm cov kev sim no.
